David Walsh (M.I.T) and Sayeed Andeshmand (Seer), Co-Chairs
This SLAS TIG is open to all experience levels, from those interested in the idea to people who print things every day. If you have ever wanted to take an idea and turn it into a real thing that you can use in the lab, then this group is for you. This community provides collaboration and resources for people thinking about getting into 3D printing and additive manufacturing, and those who already are printing on a daily basis. Share how you use 3D printing in your laboratory areas and discover how 3D printing enables highly custom and rapid prototyping.
Andrew Alt (University of Michigan) and Robert Damoiseaux (UCLA), Chairs
The mission of the Academic Drug Discovery TIG is to enable greater interaction between academia, pharmaceutical research companies, suppliers and other technical companies. Through a range of unique programs and events, the Academic Drug Discovery SIG will build bridges between the academic and applied sciences. These ties will result in better skilled candidates for industry as well as enhanced support for academic centers with programs focused on drug discovery, screening, automation and related disciplines.
Ritu Singh (C4 Therapeutics) and Amy Siu (Remix Therapeutics), Co-Chairs
The mission of the Absorption, Distribution, Metabolism and Toxicology TIG is to advance drug discovery and development by promoting the discussion and dissemination of principles, topics and ideas for the integration of higher throughput technologies with methods for determining toxicity, pharmacokinetics and metabolism. The goal is to accelerate the drug discovery pipeline and shorten the time of the development of new drugs that cure illnesses and improve quality of life. This special interest group creates a bridge and network between scientists working in the fields of preclinical research, pharmacology, pharmacokinetics and those who are the producers of combinatorial libraries.
Todd Decollo and Ruth Petersen, Co-Chairs
This TIG will create a community of scientists with backgrounds in automation, software and chemistry who have a passion for modernizing the synthesis of large and small molecules in the age of AI drug discovery. The purpose of this group is to network to solve critical issues and topics that are unsolved in this industry. Areas of focus will include guiding chemical manufacturers to follow standards in sample containers, supporting equipment manufacturers to create chemistry automation innovations, and assisting software creators to generate products that support the synthesis of many molecules. The goal of this group is to guide the industry with their collective voices to ensure the success of automation in chemistry.
Catherine Heywood (Invitae) Co-Chairs
The main purpose for this group is to provide a forum for discussion of topics relating to optimizing performance of laboratory instrumentation, including automated instrumentation. The objective is to encourage development of test procedures that should be of interest to instrument vendors and practitioners alike, and to publish these procedures as suggested “best practice” documents.
Ian Kerman, (LabVoice) and Paul Jensen (University of Michigan), Chairs
The purpose of this TIG is to:
Beth Cimini (The Broad Institute), Chair
The Data Analysis and Management TIG is dedicated to sharing best practices, experiences and expertise, and to encouraging collaboration. The group will actively address issues in the area of information technology and strategies and foster discussions, information sharing and meetings among group members. This SIG is presented in partnership with the Society of Biomolecular Imaging and Informatics (SBI2).
Marc Holbert (GlaxoSmithKline) and Rob Howes (UK Health Security Agency), Chairs
The long-term objective of the Molecular Biology and Protein Science Standards TIG is to have these standards adopted across academia and industry to provide the basis for an open database. This database will serve two major purposes: (1) improve our ability to successfully generate proteins of interest and (2) provide foundational data to explore the feasibility of building machine learning models for soluble, functional protein design.
Alison Hirukawa, Ph.D. (Drop Genie), Chair
The phenotypic drug discovery (PDD) TIG will serve as a discussion forum for the global research community to share/discuss/debate topics related to PDD research. Participants will share their experiences, perceptions, and thoughts on the advantages/disadvantages of PDD and whether/how PDD complements targeted drug discovery (TDD) strategies. Related topics such as target identification/validation, chemical diversity, chemical genomics, chemo-informatics, poly-pharmacology, translational pharmacology, biological model systems and patient tailoring are also in scope.
Markus Queisser (GlaxoSmithKline) and Anastasia Velentza (Plexium), Chairs
Proximity-induced Pharmacology for New Modalities require specialized assays and knowledge for the development and optimization of the proximity-based molecules in addition to the traditional assay and screening cascades in drug discovery. The objective of this TIG is to facilitate and promote the exchange of knowledge and experience with proximity assays i.e in Targeted Protein Degradation and Protein-Protein Interactions, setting standards and educate the field. The TIG will meet several times annually and communicate progress through SLAS. Metric for success is the agreement to standards which are adopted by the field.
Kristen Nailor (Genentech), Chair
The Sample Management TIG provides a forum for discussing sample library management issues in the modern drug discovery HTS laboratory. Sample libraries include discrete compounds, mixtures, natural products and biological samples such as tissues slices, cells, DNA, RNAi, antibodies to name just a few. With so many new types of samples needing to be stored for distribution, archiving and inventory management this forum is critical for the sample management community to come together to discuss the current and future critical topics and issues facing the industry. Topics of critical importance include sample collection (size, content and storage), Materials management (storage container compatibility, size and strength) instrumentation/automation (liquid handling, storage devices, cherry picking, compound identification LC/MS, solubility measurement) inventory software, labware leachables and database design.
Kenda Evans, Ph.D. (Agilent) and Paige Vinson, Ph.D. (Southern Research Moving Science), Chairs
The goals of the Screen Design & Assay TIG are to:
Burkhard Schaefer (SiLA Consortium) and Dana Vanderwall (Schrodinger), Chairs
The Standards Initiatives TIG promotes standardization and interoperability of instruments and data systems in the laboratory. The purpose of our session is to raise awareness of community-driven standardization efforts currently underway. It also provides a forum to foster collaboration between standards initiatives to ensure greater impact and better utilization of community resources.
Marcie Glicksman (EnClear Therapies) and Ilyas Singec (FUJIFILM Celluar Dynamics), Chairs
The mission of the Stem Cells in Drug Discovery TIG is to promote the discussion and dissemination of information on new enabling technologies related to the use of stem cells and primary cells in drug discovery. We will discuss current developments in stem cell biology, human and mouse pluripotent stem cells, and reprogrammed stem cells. This group will function to create a bridge between the network of scientists working in the fields of regenerative medicine, stem cell biology, chemical biology and drug discovery.
Raymond Price (Neuroservices Alliance), Chair
As biopharmaceutical companies seek to increase capacity, free up resources, accelerate clinical timelines, and meet business continuity requirements, technology transfer to contract research organizations (CRO) or contract manufacturing organizations (CMO) has increased dramatically. This topical interest group (TIG) will provide a platform for industry colleagues to address and discuss the challenges and key factors considered to be important for achieving successful transfer.
Debbie Bowers (BioDot, Inc.), Chair
The Women of SLAS TIG was created to provide a professional space for women in the life science and technology fields to come together and mentor, learn, and discuss the unique challenges we face as women in a STEM environment. Open to women or those supportive of women who are in various roles in the technology fields of the life science industry. Any STEM/Technology modality/role is welcome. From vendors to bench scientist, from sales to data science and more. If you are passionate, curious, or otherwise interested about the unique challenges women face in a STEM environment you are welcome.
SLAS members interested in organizing a new TIG are invited to complete an SLAS Topical Interest Group Charter Application and submit it to the SLAS Board of Directors for consideration and approval. The purpose of the application is to verify that the group has an established core of SLAS members that are interested in its formation and are willing to actively participate. The TIG Charter Application requires:
For questions about starting or participating in a Topical Interest Group, contact Gina Anzalone, Membership Manager.