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Call for Papers - Early Drug Discovery Approaches with More Physiologically Relevant Targets

Proposals accepted until November 1st!

Submit Proposals Here

SLAS Discovery Guest Editors Timothy P. Spicer, Ph.D., (Senior Scientific Director, Department of Molecular Medicine, Scripps Research) and Jonathan O'Connell, Ph.D., (Vice President, FORMA Therapeutics) invite the submission of abstracts on early drug discovery approaches with more physiologically relevant targets for publication in a 2021 Special Issue. Manuscript proposals (abstracts) will be used to select and invite papers for review and publication consideration.

Drs. Spicer and O'Connell seek high-quality, short- or full-length research reports, reviews and perspectives related to all approaches that address the use of novels models of drug discovery that reflect better approaches towards assessing more physiologically relevant human disease biology. Manuscript proposals (abstracts) are welcome from academia, industry and vendors. Areas of particular interest include, but are not limited to:

  • Complex cellular systems for drug discovery in areas such as stem cells, organoids, or the tumor microenvironment
  • Use of human iPSC models to identify or determine compound and drug efficacy aimed at neuronal, cardiac, cancer or other areas of disease
  • Phenotypic or target-based 3D drug discovery for any target area of unmet medical need
  • Methods for monitoring 3D/complex assays, e.g. lightsheet, deep-learning-based analysis or image deconvolution
  • Application of novel instrumentation and labware to provide better models of human disease
  • Rapid, flexible phenotypic approaches for translational models of human disease
  • Improved validation of molecular targets of human disease

Submit your manuscript proposal before November 1, 2019. It should include your name, contact information, affiliation, a working title and abstract (250-500 words) as an MS Word document.

Invited manuscripts will need to be completed and submitted by March 31, 2020. All submitted papers will be subject to peer-review to ensure scientific rigor, clarity of expression and integration with other contributions in the SLAS Discovery special issue. Submissions from SLAS members, nonmembers and especially attendees of the SLAS Advanced 3D Human Models and High-Content Analysis Symposium 2019 are welcome.

Publication note: After submissions are accepted, they typically publish online ahead-of-print within 30 days and become immediately searchable and citable with a DOI.

Questions? Please e-mail cdiedrich@slas.org or call +1.630.256.7527, ext. 106.