SLAS News (Jan. 24, 2019) — The SLAS Technology Ten annually showcases ten individual articles that stand out as the most innovative scientific achievements published in SLAS Technology in the past 12 months.
The 2019 SLAS Technology Ten highlights articles that address a number of areas that are recognized as important emerging technologies for life sciences laboratories and the clinic. These include technology that automates and improves isolation of subsets of cells with applications ranging from liquid biopsies to cell therapy manufacturing; technologies that improve isolation and propagation of desired cells; and improvements in ways to analyze these cells through both improved hardware and software solutions; and improved automation approaches for a wide range of assays with implications in everything from drug development to forensic science.
SLAS Technology Editor-in-Chief Edward Kai-Hua Chow, Ph.D. (National University of Singapore) thanks the 63 authors of the 2019 SLAS Technology Ten for these ground-breaking contributions and the hundreds of other researchers who also chose to share their impressive achievements in SLAS Technology in 2018. Collectively, they demonstrate the creativity and vigor with which technology continues to evolve and advance life sciences research.
Fast and Label-Free Isolation of Circulating Tumor Cells from Blood: From a Research Microfluidic Platform to an Automated Fluidic Instrument, VTX-1 Liquid Biopsy System
Clementine A. Lemaire, Sean Z. Liu, Charles L. Wilkerson, Vishnu C. Ramani, Nasim A. Barzanian, Kuo-Wei Huang, James Che, Michael W. Chiu, Meghah Vuppalapaty, Adam M. Dimmick, Dino Di Carlo, Michael L. Kochersperger, Steve C. Crouse, Stefanie S. Jeffrey, Robert F. Englert, Stephan Hengstler, Corinne Renier, Elodie Sollier-Christen (SLAS Technology 2018, 23, 16-19)
Isolation of Mitochondrial DNA from Single, Short Hairs without Roots Using Pressure Cycling Technology
By Kathryn A. Harper, Kelly A. Meiklejohn, Richard T. Merritt, Jessica Walker, Constance L. Fisher, James M. Robertson (SLAS Technology 2018, 23, 97-105)
Fully Automated Pipetting Sorting System for Different Morphological Phenotypes of Zebrafish Embryos
By Helmut Breitwieser, Thomas Dickmeis, Marcel Vogt, Marco Ferg, Christian Pylatiuk (SLAS Technology 2018, 23, 128-133)
Theranostic Nanoparticles for Tracking and Monitoring Disease State
By Cristina Zavaleta, Dean Ho, Eun Ji Chung (SLAS Technology 2018, 23, 281-293)
Quantitative Analysis of a Multiplexed Immunofluorescence Panel in T-Cell Lymphoma
By Siok-Bian Ng, Shuangyi Fan, Shoa-Nian Choo, Michal Hoppe, Hoang Mai Phuong, Sanjay De Mel, Anand D. Jeyasekharan (SLAS Technology 2018, 23, 252-258)
Identification of Angiogenesis Inhibitors Using a Co-Culture Cell Model in a High-Content and High-Throughput Screening Platform
By Shuaizhang Li, Chia-Wen Hsu, Srilatha Sakamuru, Chaozhong Zou, Ruili Huang, Menghang Xia (SLAS Technology 2018, 23, 217-225)
Deterministic Lateral Displacement: The Next-Generation CAR T-Cell Processing?
By Roberto Campos-González, Alison M. Skelley, Khushroo Gandhi, David W. Inglis, James C. Sturm, Curt I. Civin, Tony Ward (SLAS Technology 2018, 23, 338-351)
Continuous and Quantitative Purification of T-Cell Subsets for Cell Therapy Manufacturing Using Magnetic Ratcheting Cytometry
By Coleman Murray, Edward Pao, Andrew Jann, Da Eun Park, Dino Di Carlo (SLAS Technology 2018, 23, 326-337)
Achieving Reproducibility and Closed-Loop Automation in Biological Experimentation with an IoT-Enabled Lab of the Future
By Ben Miles, Peter L. Lee (SLAS Technology 2018, 23, 432-439)
Improved Fluorescence Methods for High-Throughput Protein Formulation Screening
By Yangjie Wei, Nicholas R. Larson, Siva K. Angalakurthi, C. Russell Middaugh (SLAS Technology 2018, 23, 516-528)
The 2019 SLAS Technology Ten can be accessed for free at http://journals.sagepub.com/doi/full/10.1177/2472630318812656. For more information about SLAS and its journals, visit www.slas.org/journals.
SLAS (Society for Laboratory Automation and Screening) is an international community of 18,000 professionals and students dedicated to life sciences discovery and technology. The SLAS mission is to bring together researchers in academia, industry and government to advance life sciences discovery and technology via education, knowledge exchange and global community building. For more information, visit www.slas.org.
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