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Special Issue: Engineering Innovations for Fundamental Biology and Translational Medicine

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Guest Editors
Soojung Claire Hur, Ph.D.
Deok-Ho Kim, Ph.D.


In this special issue of SLAS Technology, the editors showcase reviews and original research reports addressing the accuracy in diagnostic and prognostic tests performed on the patient-derived specimen, an emerging technology demand for personalized medicine.

Soojung Claire Hur, Ph.D., is Clare Boothe Luce Assistant Professor in the Department of Mechanical Engineering at Johns Hopkins Whiting School of Engineering, and an expert in microfluidics. Deok-Ho Kim, Ph.D., is faculty in the Department of Biomedical Engineering and Department of Medicine at the Johns Hopkins University School of Medicine.

Topics include the role of microfluidic technology in patient-specific information collection and endeavors to integrate innovative technologies with existing clinical workflows through automation and miniaturization for expedited translation.

Specifically, Mosfera A. Chowdury emphasizes the importance of ex vivo hematologic tumor models. Pan Zhang provides comprehensive reviews on advancement in technology development and their limitations for effective isolation of nanoscale, nearly-neutrally buoyant, heterogeneous vesicles. Holly T. Reardon reports an automated workflow of activity-based protein profiling that is integrated with clinical laboratory technology for accurate and fast measurements of drug-target interaction in vivo. Stephan Fox discusses automated multi-layered artificial skin fabrication as demonstrated by the injection molding process. Maedeh Mohammadifar reports a disposable, self-powered, and automated glucose-level sensor from urine samples as a non-invasive alternative to blood-based monitoring. David Pereira describes the design guideline for leading phases in the aqueous two-phase system (ATPS) for biomarker partitioning and concentration to improve the sensitivity of paper-based lateral-flow immunoassays. Christian Wiraja reports on the utility of framework nucleic acids as drug penetration agents through the skin barrier.

Along with the above authors from Binghamton University, Nanyang Technological University, National University of Singapore, University of California, University of Toronto, and ETH Zürich, the editors share this special issue to report recent advancement in technologies to initiate broad communications, facilitating further innovations to shift the healthcare paradigm closer to more predictive, preventive and personalized medicine.


Soojung Claire Hur, Ph.D.

SLAS publishes two PubMed:MEDLINE-indexed journals and accepts manuscripts on an ongoing basis from members and non-members.  > READ MORE

September 23, 2019