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Special Issue: Membrane Proteins: New Approaches to Probes, Technologies and Drug Design


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Veli-Pekka Jaakola, Ph.D.
Head of Structural Biology
Confo Therapeutics
Zwijnaarde, Belgium


Veli-Pekka Jaakola is guest editor of SLAS Discovery’s two-part special issue, “Membrane Proteins: New Approaches to Probes, Technologies and Drug Design.” His co-guest editor, Mariafrancesca Scalise, joins him in this effort and led Part I in this special issue. This special issue presents various novel strategies to study and characterize membrane proteins relevant to both physiological and pathological conditions. Part I of the special issue provided an overview of the status artis, with regard to knowledge of transporters and channels responsible for the traffic of different metabolites and on the activity of certain cell surface receptors. Part II focuses on the technologies required to develop chemical/biological applications for these important drug targets as well as enable the identification of novel chemical matter for lead optimization.

Jaakola received his Ph.D. from the Institute of Biotechnology, University of Helsinki (Finland). After postdoctoral studies on structural biology of human adenosine A2A receptor with Professor Raymond C. Stevens at the Scripps Research Institute (La Jolla, CA, USA), Jaakola joined the Oulu Biocenter, University of Oulu (Finland) as a junior group leader in 2009; and later in 2011 as adjunct professor, biochemistry and molecular medicine. In 2013 he moved to the NIBR Novartis (Basel, Switzerland) as membrane protein lab head.

Jaakola very recently joined Confo Therapeutics (Ghent, Belgium) as head of structural biology, continuing work on structural biology, structure-based drug discovery and development for GPCR targets. Jaakola has more than 30 publications, including journal papers, book chapters and reviews.



Other SLAS Publications

Rehan S, Shahid S, Slaminen T. A., Jaakola V. P. Current Progress on Equilibrative Nucleoside Transporter Function and Inhibitor Design. SLAS Discov. Online publication Sept. 10, 2019. doi: 10.1177/2472555219870123.

SLAS publishes two PubMed:MEDLINE-indexed journals and accepts manuscripts on an ongoing basis from members and non-members.  > READ MORE

November 21, 2019